Background

The COVID-19 global pandemic has highlighted the great demand for antimicrobial/antiviral coatings to impede viral transmission. Over the last decade, several reports described the introduction of antimicrobial/antiviral coatings that were applied to different surfaces. However, their widespread application is still not realized, especially in developing countries. Worldwide, millions are affected annually by disease transmission from contaminated surfaces especially in healthcare facilities. No represents a public health risk, but also a huge economic burden.

Contaminated surfaces were proven as one of the main sources for disease transmission to humans. During Covid-19 pandemic, the utilization of disinfectants has skyrocketed, however, most disinfectants are short acting solutions. There is a need for continuous surface decontamination using a coating spray that can deposit a disinfecting layer with sustained antibacterial/antiviral effect to both reduce transmission of infections as well as avoid development of bacterial resistance. An easily applied, low cost and long-acting (days to weeks) antimicrobial disinfectant would be highly accessible, reduce the need for repeated applications, and dramatically reduce disease transmission via contaminated surfaces.

Technology Overview

NanoGuard is a surface coating effective against a broad range of nosocomial infections. NanoGuard spray can be applied by individuals onto different surfaces in hospitals, universities, and homes to eliminate microbial communities and prevent disease transmission. NanoGuard is an easy-to-apply nanomaterial-based coating spray that can deposit a layer with long-acting antimicrobial effec, significantly reducing the cost of disinfection, as well as, avoiding bacterial resistance. In addition, the antimicrobial effect is expected to last up to two weeks. NanoGuard represents an innovative, cost effective, safe technology via nanoencapsulation of benzoyl peroxide, a radical-generating compound, and benzalkonium chloride into polymethylmethacrylate (PMMA) adhesive nanoparticles. These nanocapsules loaded with two antimicrobial ingredients and prepared in isopropyl alcohol, demonstrated prolonged release of free radicals and increased adhesion to surfaces thus prolonging the antiviral/antibacterial activity. NanoGuard spray was proven effective on different surfaces and against different bacterial strain including Pseudomonas aeruginosa, as well as infectious bronchial virus.

Benefits

Effective antiviral/antibacterial coating on different surfaces.
Low cost product prepared using inexpensive materials and relatively simple synthesis procedures.
Long acting (up to two weeks) nanoformula containing two disinfectants.
Available in different packaging sizes (200-1000 mL).

Applications

Nano-Guard spray is an antimicrobial coating spray that can be easily applied to different surfaces in various sectors including various surfaces at hospitals, public spaces, offices, schools and restaurants. The spray can easily be used to and sprayed on medical tools in the dental sector, various instruments and machinery and onto several textiles.

NANOGUARD: Long-Acting Antimicrobial Coating Nanomaterial and Methods for Preparation and Application to Surfaces

Patents

IP Status